Research We understand that cutting-edge research is vital to developments in patient care and treatment, which is why the research we support, is of the highest quality collaborations between clinicians, local universities and hospital staff in order to produce internationally recognised research that directly benefits patients. Whether it is pioneering research into Stem Cell Therapies that have enabled patients with multiple sclerosis to walk again, testing new medications for polycystic kidney disease or finding a cure for the terminal blood cancer myeloma, your support is helping our patients live longer and more comfortably by finding cures, more effective treatments and earlier methods of diagnosis across healthcare. Thanks to generous supporters like you, last year alone, £225,000 was spent on innovative medical research. Kidney research in Sheffield ADPKD (Autosomal Dominant Polycystic Kidney Disease) is one of the most common inherited life-threatening conditions in the UK with 1 to 2 people in every 1,000 born with the disease. ADPKD causes fluid-filled sacs (cysts) to form on the kidneys, normally in late childhood. These cysts grow over time, causing the kidneys to increase to around 4 times their normal size. The cysts eventually lead to kidney failure, meaning regular dialysis or a kidney transplant for the patient. Those with ADPKD can also suffer from other symptoms such as high blood pressure, stomach pain and bleeding in the brain, making them more at risk from strokes and heart attacks. Professor Albert Ong one of the consultants at Sheffield Teaching Hospitals is the leading researcher in this field nationally and is internationally recognised for his role in this research.